license, base_model, tags, datasets, language, pipeline_tag, library_name
license base_model tags datasets language pipeline_tag library_name
llama3.2 meta-llama/Llama-3.2-1B
medical
healthcare
knowledge-distillation
distillation
llama
llama-3.2
lightweight
clinical-nlp
MohamedAhmedAE/Med_LLaMa3_fine-tuning_dataset
en
text-generation transformers

distil_Med42_8B_Llama-3.2-1B

A 1B-parameter medical language model distilled from Llama3-Med42-8B into a Llama-3.2-1B student, using the framework from the paper "DistilLLM-Med: A Lightweight Medical Language Model through Knowledge Distillation" (IEEE ICICIS 2025).

About the paper

DistilLLM-Med: A Lightweight Medical Language Model through Knowledge Distillation Mohamed Abo El-Enen, Sally Saad, Taymoor Nazmy — Faculty of Computer and Information Sciences, Ain Shams University, Cairo, Egypt. Published in 2025 IEEE Twelfth International Conference on Intelligent Computing and Information Systems (ICICIS). IEEE Xplore

The paper distills medical expertise from two specialized teacher models — MedGemma-4B (referred to as "MedGemini-4B" in the paper text, citing Sellergren et al.'s MedGemma technical report) and Llama3-Med42-8B — into a single lightweight LLaMA 3.2-1B student, using temperature-scaled KL-divergence distillation, specialty-weighted losses, and attention-map alignment. The resulting student retains 89.3% of teacher token-level accuracy while cutting parameters by 75%, reaching 47.7% average accuracy on MMLU-Medical (67.8% of the Med42-8B teacher's 72.6%) and 59.5 tokens/sec inference throughput.

Model family

This checkpoint is one of four sibling distilled models trained in this project, all with a Llama-3.2-1B student:

Model Teacher Student base Notebook
distil_med42_8B_Llama-3.2-1B-Instruct Med42-8B Llama-3.2-1B-Instruct Train_Distil_Med42_LLama_Transformer.ipynb
distil_Med42_8B_Llama-3.2-1B (this model) Med42-8B Llama-3.2-1B Train_Distil_Med42_LLama_Transformer.ipynb
distil_llama_3_8B_Llama-3.2-1B Meta-Llama-3-8B Llama-3.2-1B Distil_LLama_LLama.ipynb
distil_MedGemma_4B_Llama-3.2-1B MedGemma-4B Llama-3.2-1B Train_Distil_MedGemma_LLama.ipynb

Method

Because Med42-8B and Llama-3.2-1B are both built on the Llama-3 tokenizer (128,256 shared vocabulary tokens), this run distills directly on logits with no vocabulary-projection layer needed (unlike the MedGemma run, which has a mismatched vocabulary).

The training objective combines four components, following the paper's Eq. (1)(7):

  1. Temperature-scaled KL distillationL_KD = α·L_CE(y, p_S) + (1-α)·L_KL(p_T^τ, p_S^τ), with α = 0.7 (favoring the soft-label/KL term over the hard-label cross-entropy term).
  2. Progressive temperature scheduling — softmax temperature τ decays exponentially from τ₀ = 8 to τ_final = 1 over the first 50,000 steps (τ(t) = τ₀·exp(-γt)), so the student first learns broad relationships between similar conditions before sharpening toward confident predictions.
  3. Specialty-weighted loss — per-specialty weights w_s re-balance the KL loss across medical subdomains (e.g., cardiology vs. dermatology) so that no single specialty dominates training.
  4. Attention-map alignment — an auxiliary Frobenius-norm loss L_att pulls the student's per-layer, per-head attention matrices toward the teacher's, so the student learns where the teacher looks (e.g., key symptoms in a vignette), not just what it outputs.

Total loss: L_total = L_weighted + β·L_att + λ‖W_S‖² (β ≈ 0.10.3, λ = weight decay).

Training setup (from the paper)

Hardware 2× NVIDIA T4 (15GB each, ~30GB total)
Optimizer AdamW, lr = 1e-6, weight decay = 0.01
Batch size 1 (+ gradient accumulation)
Precision Teacher: 4-bit NF4 quantized (bitsandbytes, double quantization, fp16 compute) · Student: full fp16
Temperature schedule τ₀ = 8 → τ_final = 1, exponential decay over 50,000 steps
α (KD/CE balance) 0.7
Training extent ~0.6 epoch over the unified corpus (per the paper)
Checkpoint on this Hub repo Global step 80,118 (save_every_steps = 5000)

Config as logged for this checkpoint on the Hub:

{
  "alpha": 0.7, "temperature": 4, "accumulation_steps": 1, "hidden_dim": 1024,
  "learning_rate": 1e-06, "num_epochs": 10,
  "teacher_vocab_size": 128256, "student_vocab_size": 128256,
  "save_every_steps": 5000, "attention_distill": true, "feature_matching": true,
  "progressive_unfreezing": true, "adaptive_temperature": true, "layer_wise_distill": true,
  "attention_loss_weight": 0.05, "feature_loss_weight": 0.1,
  "min_temperature": 1.0, "max_temperature": 8.0, "unfreeze_schedule": "linear"
}

Full implementation (loss functions, projection layers, training loop) is in Train_Distil_Med42_LLama_Transformer.ipynb.

Training data

The unified training corpus merges 18 established medical benchmarks (~1.51.65M samples after cleaning) into a single instructionresponse format, including:

  • MMLU (medical subtasks) and MedMCQA — multiple-choice medical exam questions
  • PubMedQA and COVID-QA — context-grounded biomedical QA
  • ChatDoctor and MIMIC-III — real-world clinical dialogues and notes
  • Medical Meadow and MedQuAD — structured instructional/expert-curated Q&A

Preprocessing deduplicated samples, truncated to a 1024-token limit, normalized medical abbreviations (via MeDAL mappings), and segmented long clinical notes (e.g., MIMIC-III) into coherent chunks. Benchmark test sets were excluded from training to keep evaluation fair. The processed/published version of this corpus is on the Hub as Med_LLaMa3_fine-tuning_dataset (1.64M train / 14.4k validation rows), with an instruction / input / context / output / choices / type (QA / MCQ / CASE) schema.

Results (from the paper)

The paper reports two distilled variants ("Experiment 1" and "Experiment 2") evaluated against both teachers and the untrained baseline. The paper does not explicitly label which experiment number maps to which Hub checkpoint — treat the numbers below as the project's overall benchmark results rather than a guaranteed one-to-one match with this specific file. Distilled "Experiment 1" is the paper's best/full-framework model.

MMLU-Medical accuracy:

Task LLaMA 3.2-1B (base) MedGemma-4B Llama3-Med42-8B Distilled Exp. 1 Distilled Exp. 2
Anatomy 49.6% 23.0% 74.1% 51.1% 49.6%
Clinical Knowledge 35.9% 22.6% 75.1% 49.1% 44.5%
College Biology 38.2% 26.4% 82.6% 50.0% 41.0%
College Medicine 33.5% 24.3% 68.8% 33.0% 38.2%
Medical Genetics 41.0% 34.0% 77.0% 45.0% 49.0%
Nutrition 42.2% 20.3% 73.9% 56.2% 51.6%
Professional Medicine 37.9% 17.7% 77.6% 55.2% 48.9%
Virology 38.6% 25.9% 51.8% 42.2% 34.9%
Average 39.6% 24.3% 72.6% 47.7% 44.7%

The best distilled model reaches 67.8% of the Med42-8B teacher's accuracy and a 20.5% relative improvement over the base LLaMA 3.2-1B.

MedAlpaca (medical-meadow-medical-flashcards) generation quality:

Metric Med42-8B MedGemma-4B LLaMA 3.2-1B (base) Distilled Exp. 1 Distilled Exp. 2
ROUGE-1 0.310 0.178 0.171 0.212 0.209
ROUGE-2 0.183 0.093 0.094 0.139 0.130
ROUGE-L 0.267 0.149 0.150 0.179 0.170
BLEU 0.071 0.026 0.026 0.037 0.034
Token accuracy 0.537 0.482 0.495 0.505 0.510

Average retention of the Med42-8B teacher's quality: 63.1% (up to 76.1% on ROUGE-2).

Compute efficiency:

Model Params (B) Memory (GB) Speed (tok/s) Latency (ms)
Llama3-Med42-8B (teacher) 8.03 5.32 49.7 1006.0
MedGemma-4B (teacher) 4.97 9.75 33.6 1486.6
LLaMA 3.2-1B (base) 1.24 7.68 102.7 487.0
Distilled LLaMA 3.2-1B 1.24 7.68 59.5 841.0

Ablation study (contribution of each component, MMLU-Medical average):

Variant MMLU Acc. Δ vs. base
LLaMA 3.2-1B (base) 39.6%
A: Baseline KD 42.3% +2.7
B: A + Progressive Temperature 44.7% +5.1
C: B + Specialty Weighting 46.5% +6.9
D: C + Attention Alignment (full model) 47.7% +8.1

Independent medical-expert review of 89 model answers found most responses (70/89) more detailed and context-rich than reference answers, but flagged 19/89 with critical factual errors (misdiagnoses, incorrect mechanisms) — underscoring that the model requires expert oversight and is not a standalone diagnostic tool.

Usage

from transformers import AutoModelForCausalLM, AutoTokenizer
import torch

model_id = "MohamedAhmedAE/distil_Med42_8B_Llama-3.2-1B"

tokenizer = AutoTokenizer.from_pretrained(model_id)
model = AutoModelForCausalLM.from_pretrained(
    model_id,
    torch_dtype=torch.float16,
    device_map="auto",
)

prompt = "What are some possible causes of low PTH and high calcium levels?"
inputs = tokenizer(prompt, return_tensors="pt").to(model.device)
outputs = model.generate(**inputs, max_new_tokens=200, do_sample=False)
print(tokenizer.decode(outputs[0], skip_special_tokens=True))

This is a base/completion-style checkpoint (no chat template registered on the Hub). For chat-style interaction, see distil_med42_8B_Llama-3.2-1B-Instruct.

Intended use & limitations

  • Research use in efficient/lightweight medical NLP and knowledge-distillation studies; suitable for edge/low-resource deployment experiments.
  • Not a certified clinical tool. The paper's own expert review found critical errors in ~21% of sampled answers (misdiagnoses, incorrect mechanisms). Always require qualified human oversight before acting on any output.
  • Distillation training only reached ~0.6 epoch over the corpus — treat as a research checkpoint, not a fully converged production model.
  • Inherits any biases present in the teacher model (Med42-8B) and in the 18-source training corpus.

License

Released under the Llama 3.2 Community License (matches the student base, meta-llama/Llama-3.2-1B). Since Med42-8B was used as a distillation teacher, also review the license terms on m42-health/Llama3-Med42-8B (Llama 3 Community License family) before downstream/commercial use.

Citation

@inproceedings{aboelenein2025distilllmmed,
  title     = {DistilLLM-Med: A Lightweight Medical Language Model through Knowledge Distillation},
  author    = {Abo El-Enen, Mohamed and Saad, Sally and Nazmy, Taymoor},
  booktitle = {2025 IEEE Twelfth International Conference on Intelligent Computing and Information Systems (ICICIS)},
  year      = {2025},
  publisher = {IEEE},
  url       = {https://ieeexplore.ieee.org/document/11313220/}
}
Description
Model synced from source: MohamedAhmedAE/distil_Med42_8B_Llama-3.2-1B
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