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Model: khazarai/Bio-8B-it Source: Original Platform
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README.md
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README.md
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---
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base_model: unsloth/Qwen3-8B
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tags:
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- text-generation-inference
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- transformers
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- unsloth
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- qwen3
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- sft
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license: apache-2.0
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language:
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- en
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datasets:
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- bio-nlp-umass/bioinstruct
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pipeline_tag: text-generation
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library_name: transformers
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---
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# khazarai/Bio-8B-it
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## Model Description
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Bio-8B-it is an 8B parameter biomedical instruction-tuned language model built on top of Qwen 3-8B.
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The model was fine-tuned using Supervised Fine-Tuning (SFT) with QLoRA via the PEFT framework.
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This model is optimized for biomedical and clinical NLP instruction-following tasks, including:
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- Biomedical question answering
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- Clinical text summarization
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- Information extraction
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- Clinical trial eligibility assessment
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- Differential diagnosis reasoning
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**Base Model**
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- Base: Qwen3-8B
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- Architecture: Decoder-only Transformer
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- Parameter count: 8B
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**Fine-Tuning Method**
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- Technique: Supervised Fine-Tuning (SFT)
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- Parameter-efficient tuning: QLoRA (PEFT)
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- Base model loading: 4-bit / 8-bit quantization during training
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- Final merged model: 16-bit full-precision weights
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- Training objective: Instruction-following adaptation for biomedical tasks
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- QLoRA enables efficient fine-tuning by freezing base weights and training low-rank adapters, which are later merged into the full model.
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## Dataset Overview
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- Total samples: 25,000 instruction–response pairs
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- Generation method: GPT-4 generated synthetic instruction tuning dataset
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- Inspired by: Self-Instruct methodology
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- Seed tasks: 80 manually constructed biomedical tasks
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- The dataset was automatically expanded by prompting GPT-4 with randomly selected seed examples to generate diverse biomedical instruction data.
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### Intended Use
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This model is intended for:
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- Biomedical NLP research
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- Clinical text processing experiments
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- Instruction-following biomedical assistants
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- Academic evaluation on BioMedical NLP tasks
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### Out-of-Scope Use
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This model is not intended for:
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- Direct clinical decision-making
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- Real-world medical diagnosis
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- Prescribing medication
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- Deployment in safety-critical healthcare systems
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- It should not replace licensed medical professionals.
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### How to Get Started with the Model
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```python
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from transformers import AutoTokenizer, AutoModelForCausalLM
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tokenizer = AutoTokenizer.from_pretrained("khazarai/Bio-8B-it")
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model = AutoModelForCausalLM.from_pretrained(
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"khazarai/Bio-8B-it",
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device_map={"": 0}
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)
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question = """
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Describe how to properly perform a hand hygiene using an alcohol-based hand sanitizer.
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"""
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messages = [
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{"role" : "user", "content" : question}
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]
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text = tokenizer.apply_chat_template(
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messages,
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tokenize = False,
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add_generation_prompt = True,
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enable_thinking = False,
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)
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from transformers import TextStreamer
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_ = model.generate(
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**tokenizer(text, return_tensors = "pt").to("cuda"),
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max_new_tokens = 1400,
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temperature = 0.7,
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top_p = 0.8,
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top_k = 20,
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streamer = TextStreamer(tokenizer, skip_prompt = True),
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)
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```
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Citation
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If you use this model, please cite the original BioInstruct paper:
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```
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@article{Tran2024Bioinstruct,
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author = {Tran, Hieu and Yang, Zhichao and Yao, Zonghai and Yu, Hong},
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title = {BioInstruct: instruction tuning of large language models for biomedical natural language processing},
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journal = {Journal of the American Medical Informatics Association},
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year = {2024},
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doi = {10.1093/jamia/ocae122}
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}
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```
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