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Model: TrialPanorama/LLaMA-3-8B-TP
Source: Original Platform
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2026-05-28 11:49:17 +08:00
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*.safetensors filter=lfs diff=lfs merge=lfs -text
*.bin filter=lfs diff=lfs merge=lfs -text
*.pt filter=lfs diff=lfs merge=lfs -text
*.pth filter=lfs diff=lfs merge=lfs -text
*.ckpt filter=lfs diff=lfs merge=lfs -text
tokenizer.json filter=lfs diff=lfs merge=lfs -text

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---
license: apache-2.0
base_model: meta-llama/Meta-Llama-3-8B
tags:
- trialpanorama
- clinical-trials
- sample-size-estimation
- rlvr
- reinforcement-learning
- llama-3
language:
- en
pipeline_tag: text-generation
---
# LLaMA-3-8B-TP
This model is fine-tuned from [Meta-Llama-3-8B-Instruct](https://huggingface.co/meta-llama/Meta-Llama-3-8B-Instruct) by using [TrialPanorama dataset](https://huggingface.co/datasets/TrialPanorama/Dataset) for clinical trials.
## Model Details
- **Base Model**: Meta-Llama-3-8B-Instruct
- **Fine-tuning Method**: Two-stage training
- Stage 1: Supervised Fine-Tuning (SFT) for knowledge injection
- Stage 2: RLVR (Reinforcement Learning with Verifiable Reward)
## Usage
### Basic Usage with Transformers
```python
from transformers import AutoModelForCausalLM, AutoTokenizer
import torch
# Load model and tokenizer
model_name = "TrialPanorama/LLaMA-3-8B-TP"
tokenizer = AutoTokenizer.from_pretrained(model_name)
model = AutoModelForCausalLM.from_pretrained(
model_name,
torch_dtype=torch.bfloat16,
device_map="auto"
)
# Prepare input (a toy example)
prompt = """Given the following clinical trial information, estimate the required sample size:
[Input Information]
Please provide the estimated sample size and reasoning."""
# Generate response
inputs = tokenizer(prompt, return_tensors="pt").to(model.device)
outputs = model.generate(
**inputs,
max_new_tokens=512,
temperature=0.6,
top_p=0.95,
do_sample=True
)
response = tokenizer.decode(outputs[0], skip_special_tokens=True)
print(response)
```
### Usage with vLLM (Recommended for Production)
```python
from vllm import LLM, SamplingParams
# Initialize vLLM
llm = LLM(
model="TrialPanorama/LLaMA-3-8B-TP",
tensor_parallel_size=1,
dtype="bfloat16"
)
# Set sampling parameters
sampling_params = SamplingParams(
temperature=0.6,
top_p=0.95,
max_tokens=512
)
# Generate
prompts = ["Your sample size estimation prompt here"]
outputs = llm.generate(prompts, sampling_params)
for output in outputs:
print(output.outputs[0].text)
```
## Citation
If you use this model in your research, please cite:
```bibtex
@article{wang2025trialpanorama,
title = {Developing Large Language Models for Clinical Research Using One Million Clinical Trials},
author = {Wang, Zifeng and Lin, Jiacheng and Jin, Qiao and Gao, Junyi and Pradeepkumar, Jathurshan and Jiang, Pengcheng and Lu, Zhiyong and Sun, Jimeng},
journal = {arXiv preprint arXiv:2505.16097},
year = {2025},
url = {https://arxiv.org/abs/2505.16097}
}
```

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{{- bos_token }}
{%- if custom_tools is defined %}
{%- set tools = custom_tools %}
{%- endif %}
{%- if not tools_in_user_message is defined %}
{%- set tools_in_user_message = true %}
{%- endif %}
{%- if not date_string is defined %}
{%- if strftime_now is defined %}
{%- set date_string = strftime_now("%d %b %Y") %}
{%- else %}
{%- set date_string = "26 Jul 2024" %}
{%- endif %}
{%- endif %}
{%- if not tools is defined %}
{%- set tools = none %}
{%- endif %}
{#- This block extracts the system message, so we can slot it into the right place. #}
{%- if messages[0]['role'] == 'system' %}
{%- set system_message = messages[0]['content']|trim %}
{%- set messages = messages[1:] %}
{%- else %}
{%- set system_message = "" %}
{%- endif %}
{#- System message #}
{{- "<|start_header_id|>system<|end_header_id|>\n\n" }}
{%- if tools is not none %}
{{- "Environment: ipython\n" }}
{%- endif %}
{{- "Cutting Knowledge Date: December 2023\n" }}
{{- "Today Date: " + date_string + "\n\n" }}
{%- if tools is not none and not tools_in_user_message %}
{{- "You have access to the following functions. To call a function, please respond with JSON for a function call." }}
{{- 'Respond in the format {"name": function name, "parameters": dictionary of argument name and its value}.' }}
{{- "Do not use variables.\n\n" }}
{%- for t in tools %}
{{- t | tojson(indent=4) }}
{{- "\n\n" }}
{%- endfor %}
{%- endif %}
{{- system_message }}
{{- "<|eot_id|>" }}
{#- Custom tools are passed in a user message with some extra guidance #}
{%- if tools_in_user_message and not tools is none %}
{#- Extract the first user message so we can plug it in here #}
{%- if messages | length != 0 %}
{%- set first_user_message = messages[0]['content']|trim %}
{%- set messages = messages[1:] %}
{%- else %}
{{- raise_exception("Cannot put tools in the first user message when there's no first user message!") }}
{%- endif %}
{{- '<|start_header_id|>user<|end_header_id|>\n\n' -}}
{{- "Given the following functions, please respond with a JSON for a function call " }}
{{- "with its proper arguments that best answers the given prompt.\n\n" }}
{{- 'Respond in the format {"name": function name, "parameters": dictionary of argument name and its value}.' }}
{{- "Do not use variables.\n\n" }}
{%- for t in tools %}
{{- t | tojson(indent=4) }}
{{- "\n\n" }}
{%- endfor %}
{{- first_user_message + "<|eot_id|>"}}
{%- endif %}
{%- for message in messages %}
{%- if not (message.role == 'ipython' or message.role == 'tool' or 'tool_calls' in message) %}
{{- '<|start_header_id|>' + message['role'] + '<|end_header_id|>\n\n'+ message['content'] | trim + '<|eot_id|>' }}
{%- elif 'tool_calls' in message %}
{%- if not message.tool_calls|length == 1 %}
{{- raise_exception("This model only supports single tool-calls at once!") }}
{%- endif %}
{%- set tool_call = message.tool_calls[0].function %}
{{- '<|start_header_id|>assistant<|end_header_id|>\n\n' -}}
{{- '{"name": "' + tool_call.name + '", ' }}
{{- '"parameters": ' }}
{{- tool_call.arguments | tojson }}
{{- "}" }}
{{- "<|eot_id|>" }}
{%- elif message.role == "tool" or message.role == "ipython" %}
{{- "<|start_header_id|>ipython<|end_header_id|>\n\n" }}
{%- if message.content is mapping or message.content is iterable %}
{{- message.content | tojson }}
{%- else %}
{{- message.content }}
{%- endif %}
{{- "<|eot_id|>" }}
{%- endif %}
{%- endfor %}
{%- if add_generation_prompt %}
{{- '<|start_header_id|>assistant<|end_header_id|>\n\n' }}
{%- endif %}

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{
"architectures": [
"LlamaForCausalLM"
],
"attention_bias": false,
"attention_dropout": 0.0,
"bos_token_id": 128000,
"dtype": "bfloat16",
"eos_token_id": 128009,
"head_dim": 128,
"hidden_act": "silu",
"hidden_size": 3072,
"initializer_range": 0.02,
"intermediate_size": 8192,
"max_position_embeddings": 131072,
"mlp_bias": false,
"model_type": "llama",
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"num_hidden_layers": 28,
"num_key_value_heads": 8,
"pad_token_id": 128009,
"pretraining_tp": 1,
"rms_norm_eps": 1e-05,
"rope_scaling": {
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"high_freq_factor": 4.0,
"low_freq_factor": 1.0,
"original_max_position_embeddings": 8192,
"rope_type": "llama3"
},
"rope_theta": 500000.0,
"tie_word_embeddings": true,
"torch_dtype": "float32",
"transformers_version": "4.55.4",
"use_cache": false,
"vocab_size": 128256
}

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"pad_token_id": 128009,
"temperature": 0.6,
"top_p": 0.9,
"transformers_version": "4.55.4"
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{
"additional_special_tokens": [
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