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Model: TrialPanorama/LLaMA-3-8B-TP Source: Original Platform
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*.safetensors filter=lfs diff=lfs merge=lfs -text
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*.bin filter=lfs diff=lfs merge=lfs -text
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*.pt filter=lfs diff=lfs merge=lfs -text
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*.pth filter=lfs diff=lfs merge=lfs -text
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*.ckpt filter=lfs diff=lfs merge=lfs -text
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tokenizer.json filter=lfs diff=lfs merge=lfs -text
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README.md
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README.md
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---
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license: apache-2.0
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base_model: meta-llama/Meta-Llama-3-8B
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tags:
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- trialpanorama
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- clinical-trials
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- sample-size-estimation
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- rlvr
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- reinforcement-learning
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- llama-3
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language:
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- en
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pipeline_tag: text-generation
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---
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# LLaMA-3-8B-TP
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This model is fine-tuned from [Meta-Llama-3-8B-Instruct](https://huggingface.co/meta-llama/Meta-Llama-3-8B-Instruct) by using [TrialPanorama dataset](https://huggingface.co/datasets/TrialPanorama/Dataset) for clinical trials.
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## Model Details
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- **Base Model**: Meta-Llama-3-8B-Instruct
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- **Fine-tuning Method**: Two-stage training
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- Stage 1: Supervised Fine-Tuning (SFT) for knowledge injection
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- Stage 2: RLVR (Reinforcement Learning with Verifiable Reward)
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## Usage
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### Basic Usage with Transformers
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```python
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from transformers import AutoModelForCausalLM, AutoTokenizer
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import torch
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# Load model and tokenizer
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model_name = "TrialPanorama/LLaMA-3-8B-TP"
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tokenizer = AutoTokenizer.from_pretrained(model_name)
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model = AutoModelForCausalLM.from_pretrained(
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model_name,
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torch_dtype=torch.bfloat16,
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device_map="auto"
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)
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# Prepare input (a toy example)
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prompt = """Given the following clinical trial information, estimate the required sample size:
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[Input Information]
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Please provide the estimated sample size and reasoning."""
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# Generate response
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inputs = tokenizer(prompt, return_tensors="pt").to(model.device)
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outputs = model.generate(
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**inputs,
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max_new_tokens=512,
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temperature=0.6,
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top_p=0.95,
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do_sample=True
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)
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response = tokenizer.decode(outputs[0], skip_special_tokens=True)
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print(response)
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```
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### Usage with vLLM (Recommended for Production)
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```python
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from vllm import LLM, SamplingParams
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# Initialize vLLM
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llm = LLM(
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model="TrialPanorama/LLaMA-3-8B-TP",
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tensor_parallel_size=1,
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dtype="bfloat16"
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)
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# Set sampling parameters
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sampling_params = SamplingParams(
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temperature=0.6,
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top_p=0.95,
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max_tokens=512
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)
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# Generate
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prompts = ["Your sample size estimation prompt here"]
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outputs = llm.generate(prompts, sampling_params)
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for output in outputs:
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print(output.outputs[0].text)
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```
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## Citation
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If you use this model in your research, please cite:
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```bibtex
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@article{wang2025trialpanorama,
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title = {Developing Large Language Models for Clinical Research Using One Million Clinical Trials},
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author = {Wang, Zifeng and Lin, Jiacheng and Jin, Qiao and Gao, Junyi and Pradeepkumar, Jathurshan and Jiang, Pengcheng and Lu, Zhiyong and Sun, Jimeng},
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journal = {arXiv preprint arXiv:2505.16097},
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year = {2025},
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url = {https://arxiv.org/abs/2505.16097}
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}
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```
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chat_template.jinja
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chat_template.jinja
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{{- bos_token }}
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{%- if custom_tools is defined %}
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{%- set tools = custom_tools %}
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{%- endif %}
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{%- if not tools_in_user_message is defined %}
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{%- set tools_in_user_message = true %}
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{%- endif %}
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{%- if not date_string is defined %}
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{%- if strftime_now is defined %}
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{%- set date_string = strftime_now("%d %b %Y") %}
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{%- else %}
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{%- set date_string = "26 Jul 2024" %}
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{%- endif %}
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{%- endif %}
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{%- if not tools is defined %}
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{%- set tools = none %}
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{%- endif %}
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{#- This block extracts the system message, so we can slot it into the right place. #}
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{%- if messages[0]['role'] == 'system' %}
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{%- set system_message = messages[0]['content']|trim %}
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{%- set messages = messages[1:] %}
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{%- else %}
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{%- set system_message = "" %}
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{%- endif %}
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{#- System message #}
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{{- "<|start_header_id|>system<|end_header_id|>\n\n" }}
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{%- if tools is not none %}
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{{- "Environment: ipython\n" }}
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{%- endif %}
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{{- "Cutting Knowledge Date: December 2023\n" }}
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{{- "Today Date: " + date_string + "\n\n" }}
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{%- if tools is not none and not tools_in_user_message %}
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{{- "You have access to the following functions. To call a function, please respond with JSON for a function call." }}
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{{- 'Respond in the format {"name": function name, "parameters": dictionary of argument name and its value}.' }}
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{{- "Do not use variables.\n\n" }}
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{%- for t in tools %}
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{{- t | tojson(indent=4) }}
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{{- "\n\n" }}
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{%- endfor %}
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{%- endif %}
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{{- system_message }}
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{{- "<|eot_id|>" }}
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{#- Custom tools are passed in a user message with some extra guidance #}
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{%- if tools_in_user_message and not tools is none %}
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{#- Extract the first user message so we can plug it in here #}
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{%- if messages | length != 0 %}
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{%- set first_user_message = messages[0]['content']|trim %}
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{%- set messages = messages[1:] %}
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{%- else %}
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{{- raise_exception("Cannot put tools in the first user message when there's no first user message!") }}
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{%- endif %}
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{{- '<|start_header_id|>user<|end_header_id|>\n\n' -}}
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{{- "Given the following functions, please respond with a JSON for a function call " }}
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{{- "with its proper arguments that best answers the given prompt.\n\n" }}
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{{- 'Respond in the format {"name": function name, "parameters": dictionary of argument name and its value}.' }}
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{{- "Do not use variables.\n\n" }}
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{%- for t in tools %}
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{{- t | tojson(indent=4) }}
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{{- "\n\n" }}
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{%- endfor %}
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{{- first_user_message + "<|eot_id|>"}}
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{%- endif %}
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{%- for message in messages %}
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{%- if not (message.role == 'ipython' or message.role == 'tool' or 'tool_calls' in message) %}
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{{- '<|start_header_id|>' + message['role'] + '<|end_header_id|>\n\n'+ message['content'] | trim + '<|eot_id|>' }}
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{%- elif 'tool_calls' in message %}
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{%- if not message.tool_calls|length == 1 %}
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{{- raise_exception("This model only supports single tool-calls at once!") }}
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{%- endif %}
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{%- set tool_call = message.tool_calls[0].function %}
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{{- '<|start_header_id|>assistant<|end_header_id|>\n\n' -}}
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{{- '{"name": "' + tool_call.name + '", ' }}
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{{- '"parameters": ' }}
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{{- tool_call.arguments | tojson }}
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{{- "}" }}
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{{- "<|eot_id|>" }}
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{%- elif message.role == "tool" or message.role == "ipython" %}
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{{- "<|start_header_id|>ipython<|end_header_id|>\n\n" }}
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{%- if message.content is mapping or message.content is iterable %}
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{{- message.content | tojson }}
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{%- else %}
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{{- message.content }}
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{%- endif %}
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{{- "<|eot_id|>" }}
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{%- endif %}
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{%- endfor %}
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{%- if add_generation_prompt %}
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{{- '<|start_header_id|>assistant<|end_header_id|>\n\n' }}
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{%- endif %}
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config.json
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{
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"architectures": [
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"LlamaForCausalLM"
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],
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"attention_bias": false,
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"attention_dropout": 0.0,
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"bos_token_id": 128000,
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"dtype": "bfloat16",
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"eos_token_id": 128009,
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"head_dim": 128,
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"hidden_act": "silu",
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"hidden_size": 3072,
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"initializer_range": 0.02,
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"intermediate_size": 8192,
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"max_position_embeddings": 131072,
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"mlp_bias": false,
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"model_type": "llama",
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"num_attention_heads": 24,
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"num_hidden_layers": 28,
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"num_key_value_heads": 8,
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"pad_token_id": 128009,
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"pretraining_tp": 1,
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"rms_norm_eps": 1e-05,
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"rope_scaling": {
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"factor": 32.0,
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"high_freq_factor": 4.0,
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"low_freq_factor": 1.0,
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"original_max_position_embeddings": 8192,
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"rope_type": "llama3"
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},
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"rope_theta": 500000.0,
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"tie_word_embeddings": true,
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"torch_dtype": "float32",
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"transformers_version": "4.55.4",
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"use_cache": false,
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"vocab_size": 128256
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}
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generation_config.json
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{
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"bos_token_id": 128000,
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"do_sample": true,
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"eos_token_id": [
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128009,
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128001,
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128008,
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128009
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],
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"pad_token_id": 128009,
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"temperature": 0.6,
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"top_p": 0.9,
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"transformers_version": "4.55.4"
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}
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model.safetensors
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version https://git-lfs.github.com/spec/v1
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oid sha256:688d81b764fa4b8950a03332fdc3f62cd85363fafdb4994eedbb7b1d497a1e35
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size 14427038512
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special_tokens_map.json
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{
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"additional_special_tokens": [
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"<|eom_id|>"
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],
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"bos_token": {
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"content": "<|begin_of_text|>",
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"lstrip": false,
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"normalized": false,
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"rstrip": false,
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"single_word": false
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},
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"eos_token": {
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"content": "<|eot_id|>",
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"lstrip": false,
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"normalized": false,
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"rstrip": false,
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"single_word": false
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},
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"pad_token": {
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"content": "<|eot_id|>",
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"lstrip": false,
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"normalized": false,
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"rstrip": false,
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"single_word": false
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}
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}
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tokenizer.json
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tokenizer.json
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tokenizer_config.json
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tokenizer_config.json
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