diff --git a/tests/e2e/nightly/multi_node/config/DeepSeek-R1-W8A8-longseq.yaml b/tests/e2e/nightly/multi_node/config/DeepSeek-R1-W8A8-longseq.yaml
index 0878245e..ca6681fa 100644
--- a/tests/e2e/nightly/multi_node/config/DeepSeek-R1-W8A8-longseq.yaml
+++ b/tests/e2e/nightly/multi_node/config/DeepSeek-R1-W8A8-longseq.yaml
@@ -13,7 +13,7 @@ env_common:
   HCCL_DETERMINISTIC: True
   TASK_QUEUE_ENABLE: 1
   HCCL_OP_RETRY_ENABLE: "L0:0, L1:0"
-  VLLM_MOONCAKE_ABORT_REQUEST_TIMEOUT: 480
+  VLLM_MOONCAKE_ABORT_REQUEST_TIMEOUT: 300000
 
 disaggregated_prefill:
   enabled: true
diff --git a/tests/e2e/nightly/multi_node/config/DeepSeek-V3_2-W8A8-EP-aime2025.yaml b/tests/e2e/nightly/multi_node/config/DeepSeek-V3_2-W8A8-EP-aime2025.yaml
index b3d47ca0..147e87f0 100644
--- a/tests/e2e/nightly/multi_node/config/DeepSeek-V3_2-W8A8-EP-aime2025.yaml
+++ b/tests/e2e/nightly/multi_node/config/DeepSeek-V3_2-W8A8-EP-aime2025.yaml
@@ -15,7 +15,7 @@ env_common:
   ASCEND_TRANSPORT_PRINT: 1
   ACL_OP_INIT_MODE: 1
   ASCEND_A3_ENABLE: 1
-  VLLM_MOONCAKE_ABORT_REQUEST_TIMEOUT: 480
+  VLLM_MOONCAKE_ABORT_REQUEST_TIMEOUT: 300000
   VLLM_ENGINE_READY_TIMEOUT_S: 1800
   HCCL_CONNECT_TIMEOUT: 1200
   HCCL_INTRA_PCIE_ENABLE: 1
diff --git a/tests/e2e/nightly/multi_node/config/DeepSeek-V3_2-W8A8-EP.yaml b/tests/e2e/nightly/multi_node/config/DeepSeek-V3_2-W8A8-EP.yaml
index 9c46bb56..3d3eeb64 100644
--- a/tests/e2e/nightly/multi_node/config/DeepSeek-V3_2-W8A8-EP.yaml
+++ b/tests/e2e/nightly/multi_node/config/DeepSeek-V3_2-W8A8-EP.yaml
@@ -15,7 +15,7 @@ env_common:
   ASCEND_TRANSPORT_PRINT: 1
   ACL_OP_INIT_MODE: 1
   ASCEND_A3_ENABLE: 1
-  VLLM_MOONCAKE_ABORT_REQUEST_TIMEOUT: 480
+  VLLM_MOONCAKE_ABORT_REQUEST_TIMEOUT: 300000
   VLLM_ENGINE_READY_TIMEOUT_S: 1800
   HCCL_CONNECT_TIMEOUT: 1200
   HCCL_INTRA_PCIE_ENABLE: 1