diff --git a/vllm_ascend/patch/__init__.py b/vllm_ascend/patch/__init__.py
index b4d4148d..4a1b0a16 100644
--- a/vllm_ascend/patch/__init__.py
+++ b/vllm_ascend/patch/__init__.py
@@ -452,3 +452,35 @@
 #       https://github.com/vllm-project/vllm/pull/34880
 #    Future Plan:
 #       Remove this patch when vLLM merges the PR.
+#
+# ** 21. File: worker/patch_deepseek_mtp.py**
+# ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+#   1. `vllm.model_executor.models.deepseek_v2.get_spec_layer_idx_from_weight_name` and
+#      `vllm.model_executor.models.deepseek_mtp.get_spec_layer_idx_from_weight_name`
+#    Why:
+#       When GLM5 uses rotary quant in vllm-ascend, the MTP layer needs to load an extra weight
+#       named `rot.weight`.
+#    How：
+#       If weight name starts with `rot`, return `layer_id + i` like other tensors in MTP layer.
+#    Related PR (if no, explain why):
+#       Rotary quant is a unique feature of vllm-ascend.
+#    Future Plan:
+#       Remove this patch when vllm supports rotary quant or pluggable `MultiTokenPredictorLayer`.
+#   2. `vllm.model_executor.models.deepseek_mtp.DeepSeekMultiTokenPredictorLayer`
+#    Why:
+#       When GLM5 uses rotary quant in vllm-ascend, the `previous_hidden_states` does not .
+#    How：
+#       If the target model uses rotary quant, a new linear operation is added before `ehnorm`.
+#    Related PR (if no, explain why):
+#       Rotary quant is a unique feature of vllm-ascend.
+#    Future Plan:
+#       Remove this patch when vllm supports rotary quant or pluggable `MultiTokenPredictorLayer`.
+#   3. `vllm.model_executor.models.deepseek_mtp.DeepSeekMTP._rewrite_spec_layer_name`
+#    Why:
+#       Rename `rot.weight` to match the format of weights in `DeepSeekMTP`.
+#    How：
+#       If the weight name is `rot`, rename it to `model.layers.{spec_layer}.rot.weight`.
+#    Related PR (if no, explain why):
+#       Rotary quant is a unique feature of vllm-ascend.
+#    Future Plan:
+#       Remove this patch when vllm supports rotary quant or pluggable `MultiTokenPredictorLayer`.
diff --git a/vllm_ascend/patch/worker/__init__.py b/vllm_ascend/patch/worker/__init__.py
index 1664c84a..a847cac2 100644
--- a/vllm_ascend/patch/worker/__init__.py
+++ b/vllm_ascend/patch/worker/__init__.py
@@ -44,3 +44,4 @@ import vllm_ascend.patch.worker.patch_npugraph_ex_triton  # noqa
 import vllm_ascend.patch.worker.patch_kimi_k25  # noqa
 import vllm_ascend.patch.worker.patch_draft_quarot  # noqa
 import vllm_ascend.patch.worker.patch_cudagraph  # noqa
+import vllm_ascend.patch.worker.patch_deepseek_mtp  # noqa
diff --git a/vllm_ascend/patch/worker/patch_deepseek_mtp.py b/vllm_ascend/patch/worker/patch_deepseek_mtp.py
new file mode 100644
index 00000000..bc147d74
--- /dev/null
+++ b/vllm_ascend/patch/worker/patch_deepseek_mtp.py
@@ -0,0 +1,63 @@
+import torch
+import torch.nn as nn
+import vllm
+from transformers import DeepseekV2Config, DeepseekV3Config
+from vllm.config import VllmConfig
+from vllm.model_executor.models.deepseek_mtp import DeepSeekMTP, DeepSeekMultiTokenPredictorLayer
+
+MTP_ROT_WEIGHT_NAME = "rot.weight"
+
+
+def get_spec_layer_idx_from_weight_name(config: DeepseekV2Config | DeepseekV3Config, weight_name: str) -> int | None:
+    if hasattr(config, "num_nextn_predict_layers") and config.num_nextn_predict_layers > 0:
+        layer_idx = config.num_hidden_layers
+        for i in range(config.num_nextn_predict_layers):
+            if weight_name.startswith(f"model.layers.{layer_idx + i}.") or weight_name.startswith(MTP_ROT_WEIGHT_NAME):
+                return layer_idx + i
+    return None
+
+
+class AscendDeepSeekMultiTokenPredictorLayer(DeepSeekMultiTokenPredictorLayer):
+    def __init__(self, vllm_config: VllmConfig, prefix: str) -> None:
+        super().__init__(vllm_config, prefix)
+        quant_description = getattr(vllm_config.quant_config, "quant_description", None)
+        self.is_rot_used = quant_description.get("is_rot_used", False) if quant_description is not None else False
+        self.target_model_type = vllm_config.speculative_config.target_model_config.hf_text_config.model_type
+        if self.is_rot_used and self.target_model_type == "glm_moe_dsa":
+            self.rot = nn.Linear(self.config.hidden_size, self.config.hidden_size, bias=False)
+
+    def forward(
+        self,
+        input_ids: torch.Tensor,
+        positions: torch.Tensor,
+        previous_hidden_states: torch.Tensor,
+        inputs_embeds: torch.Tensor | None = None,
+        spec_step_index: int = 0,
+    ) -> torch.Tensor:
+        assert inputs_embeds is not None
+        # masking inputs at position 0, as not needed by MTP
+        inputs_embeds = torch.where(positions.unsqueeze(-1) == 0, 0, inputs_embeds)
+        inputs_embeds = self.enorm(inputs_embeds)
+        if self.is_rot_used and self.target_model_type == "glm_moe_dsa":
+            previous_hidden_states = self.rot(previous_hidden_states)
+        previous_hidden_states = self.hnorm(previous_hidden_states)
+
+        hidden_states = self.eh_proj(torch.cat([inputs_embeds, previous_hidden_states], dim=-1))
+
+        hidden_states, residual = self.mtp_block(positions=positions, hidden_states=hidden_states, residual=None)
+        hidden_states = residual + hidden_states
+        return hidden_states
+
+
+class AscendDeepSeekMTP(DeepSeekMTP):
+    def _rewrite_spec_layer_name(self, spec_layer: int, name: str) -> str:
+        if name != MTP_ROT_WEIGHT_NAME:
+            return super()._rewrite_spec_layer_name(spec_layer, name)
+        else:
+            return f"model.layers.{spec_layer}.rot.weight"
+
+
+vllm.model_executor.models.deepseek_v2.get_spec_layer_idx_from_weight_name = get_spec_layer_idx_from_weight_name
+vllm.model_executor.models.deepseek_mtp.get_spec_layer_idx_from_weight_name = get_spec_layer_idx_from_weight_name
+vllm.model_executor.models.deepseek_mtp.DeepSeekMultiTokenPredictorLayer = AscendDeepSeekMultiTokenPredictorLayer
+vllm.model_executor.models.deepseek_mtp.DeepSeekMTP = AscendDeepSeekMTP