diff --git a/.github/workflows/pr-e2e-test.yml b/.github/workflows/pr-e2e-test.yml
index 2f4a496e6..140ab9c83 100644
--- a/.github/workflows/pr-e2e-test.yml
+++ b/.github/workflows/pr-e2e-test.yml
@@ -5,10 +5,36 @@ on:
     branches: [ main ]
     paths:
       - "python/sglang/*"
+      - "python/sglang/lang/*"
+      - "python/sglang/lang/backend/*"
+      - "python/sglang/srt/*"
+      - "python/sglang/srt/constrained/*"
+      - "python/sglang/srt/layers/*"
+      - "python/sglang/srt/layers/quantization/*"
+      - "python/sglang/srt/managers/*"
+      - "python/sglang/srt/mem_cache/*"
+      - "python/sglang/srt/model_executor/*"
+      - "python/sglang/srt/model_loader/*"
+      - "python/sglang/srt/models/*"
+      - "python/sglang/srt/openai_api/*"
+      - "python/sglang/test/*"
   pull_request:
     branches: [ main ]
     paths:
       - "python/sglang/*"
+      - "python/sglang/lang/*"
+      - "python/sglang/lang/backend/*"
+      - "python/sglang/srt/*"
+      - "python/sglang/srt/constrained/*"
+      - "python/sglang/srt/layers/*"
+      - "python/sglang/srt/layers/quantization/*"
+      - "python/sglang/srt/managers/*"
+      - "python/sglang/srt/mem_cache/*"
+      - "python/sglang/srt/model_executor/*"
+      - "python/sglang/srt/model_loader/*"
+      - "python/sglang/srt/models/*"
+      - "python/sglang/srt/openai_api/*"
+      - "python/sglang/test/*"
   workflow_dispatch:
 
 jobs: