diff --git a/python/sglang/srt/layers/moe/ep_moe/layer.py b/python/sglang/srt/layers/moe/ep_moe/layer.py
index 4e1e97713..ac1a831ac 100644
--- a/python/sglang/srt/layers/moe/ep_moe/layer.py
+++ b/python/sglang/srt/layers/moe/ep_moe/layer.py
@@ -33,10 +33,12 @@ from sglang.srt.layers.quantization.base_config import (
 )
 from sglang.srt.layers.quantization.fp8 import Fp8Config, Fp8MoEMethod
 from sglang.srt.layers.quantization.fp8_kernel import (
+    is_fp8_fnuz,
     scaled_fp8_quant,
     sglang_per_token_group_quant_fp8,
     sglang_per_token_quant_fp8,
 )
+from sglang.srt.layers.quantization.fp8_utils import normalize_e4m3fn_to_e4m3fnuz
 from sglang.srt.managers.expert_location import get_global_expert_location_metadata
 from sglang.srt.managers.expert_location_dispatch import ExpertLocationDispatchInfo
 from sglang.srt.managers.schedule_batch import global_server_args_dict
@@ -50,6 +52,7 @@ from sglang.srt.utils import (
 )
 
 _is_hip = is_hip()
+_is_fp8_fnuz = is_fp8_fnuz()
 
 if _is_hip:
     from vllm._custom_ops import scaled_fp8_quant
@@ -843,6 +846,33 @@ class Fp8EPMoEMethod(Fp8MoEMethod):
                     torch.max(layer.w13_weight_scale, dim=1).values,
                     requires_grad=False,
                 )
+            if self.block_quant:
+                # If ROCm, normalize the weights and scales to e4m3fnuz
+                if _is_fp8_fnuz:
+                    # activation_scheme: dynamic
+                    w13_weight, w13_weight_scale, _ = normalize_e4m3fn_to_e4m3fnuz(
+                        weight=layer.w13_weight,
+                        weight_scale=layer.w13_weight_scale_inv,
+                        input_scale=None,
+                    )
+                    w2_weight, w2_weight_scale, _ = normalize_e4m3fn_to_e4m3fnuz(
+                        weight=layer.w2_weight,
+                        weight_scale=layer.w2_weight_scale_inv,
+                        input_scale=None,
+                    )
+                    # Reset the parameter
+                    layer.w13_weight = torch.nn.Parameter(
+                        w13_weight, requires_grad=False
+                    )
+                    layer.w13_weight_scale_inv = torch.nn.Parameter(
+                        w13_weight_scale, requires_grad=False
+                    )
+                    layer.w13_input_scale = None
+                    layer.w2_weight = torch.nn.Parameter(w2_weight, requires_grad=False)
+                    layer.w2_weight_scale_inv = torch.nn.Parameter(
+                        w2_weight_scale, requires_grad=False
+                    )
+                    layer.w2_input_scale = None
             return
 
     def apply(