diff --git a/docs/backend/sampling_params.md b/docs/backend/sampling_params.md
index 72e03008b..3c2589f48 100644
--- a/docs/backend/sampling_params.md
+++ b/docs/backend/sampling_params.md
@@ -51,6 +51,7 @@ Please refer to our dedicated guide on [constrained decoding](./structured_outpu
 * `n: int = 1`: Specifies the number of output sequences to generate per request. (Generating multiple outputs in one request (n > 1) is discouraged; repeating the same prompts several times offers better control and efficiency.)
 * `spaces_between_special_tokens: bool = True`: Whether or not to add spaces between special tokens during detokenization.
 * `no_stop_trim: bool = False`: Don't trim stop words or EOS token from the generated text.
+* `continue_final_message: bool = False` : When enabled, the final assistant message is removed and its content is used as a prefill so that the model continues that message instead of starting a new turn. See [openai_chat_with_response_prefill.py](https://github.com/sgl-project/sglang/blob/main/examples/runtime/openai_chat_with_response_prefill.py) for examples.
 * `ignore_eos: bool = False`: Don't stop generation when EOS token is sampled.
 * `skip_special_tokens: bool = True`: Remove special tokens during decoding.
 * `custom_params: Optional[List[Optional[Dict[str, Any]]]] = None`: Used when employing `CustomLogitProcessor`. For usage, see below.
diff --git a/examples/runtime/README.md b/examples/runtime/README.md
index ecf116d1d..941863727 100644
--- a/examples/runtime/README.md
+++ b/examples/runtime/README.md
@@ -8,7 +8,9 @@ The below examples will mostly need you to start a server in a separate terminal
 * `multimodal_embedding.py`: An example how perform [multi modal embedding](Alibaba-NLP/gme-Qwen2-VL-2B-Instruct).
 * `openai_batch_chat.py`: An example how to process batch requests for chat completions.
 * `openai_batch_complete.py`: An example how to process batch requests for text completions.
-* `openai_chat_with_response_prefill.py`: An example how to [prefill](https://eugeneyan.com/writing/prompting/#prefill-claudes-responses) a response using OpenAI API.
+* **`openai_chat_with_response_prefill.py`**:
+  An example that demonstrates how to [prefill a response](https://eugeneyan.com/writing/prompting/#prefill-claudes-responses) using the OpenAI API by enabling the `continue_final_message` parameter.
+  When enabled, the final (partial) assistant message is removed and its content is used as a prefill so that the model continues that message rather  than starting a new turn. See [Anthropic's prefill example](https://docs.anthropic.com/en/docs/build-with-claude/prompt-engineering/prefill-claudes-response#example-structured-data-extraction-with-prefilling) for more context.
 * `reward_model.py`: An example how to extract scores from a reward model.
 * `vertex_predict.py`: An example how to deploy a model to [Vertex AI](https://cloud.google.com/vertex-ai?hl=en).
 
diff --git a/examples/runtime/openai_chat_with_response_prefill.py b/examples/runtime/openai_chat_with_response_prefill.py
index c80f97d11..6d803a1d1 100644
--- a/examples/runtime/openai_chat_with_response_prefill.py
+++ b/examples/runtime/openai_chat_with_response_prefill.py
@@ -1,33 +1,53 @@
 """
 Usage:
-python -m sglang.launch_server --model-path meta-llama/Llama-3.1-8B-Instruct --port 30000
-python openai_chat.py
+1) Launch the server in one terminal:
+   python -m sglang.launch_server --model-path meta-llama/Llama-3.1-8B-Instruct --port 30000
+
+2) Run this script in another terminal:
+   python openai_chat_with_response_prefill.py
+
+This example demonstrates two chat completion calls:
+- One with continue_final_message enabled (the final assistant message is used as a prefill).
+- One without continue_final_message (the final assistant message remains, starting a new turn).
 """
 
 import openai
 
 client = openai.Client(base_url="http://127.0.0.1:30000/v1", api_key="EMPTY")
 
-response = client.chat.completions.create(
-    model="meta-llama/Llama-3.1-8B-Instruct",
-    messages=[
-        {"role": "system", "content": "You are a helpful AI assistant"},
-        {
-            "role": "user",
-            "content": """
+messages = [
+    {"role": "system", "content": "You are a helpful AI assistant."},
+    {
+        "role": "user",
+        "content": """
 Extract the name, size, price, and color from this product description as a JSON object:
 
 <description>
-The SmartHome Mini is a compact smart home assistant available in black or white for only $49.99. At just 5 inches wide, it lets you control lights, thermostats, and other connected devices via voice or app—no matter where you place it in your home. This affordable little hub brings convenient hands-free control to your smart devices.
+The SmartHome Mini is a compact smart home assistant available in black or white for only $49.99.
+At just 5 inches wide, it lets you control lights, thermostats, and other connected devices via voice or app—
+no matter where you place it in your home.
+This affordable little hub brings convenient hands-free control to your smart devices.
 </description>
 """,
-        },
-        {
-            "role": "assistant",
-            "content": "{\n",
-        },
-    ],
+    },
+    {"role": "assistant", "content": "{\n"},
+]
+
+# Calling the API with continue_final_message enabled.
+print("=== Prefill with continue_final_messagem ===")
+response_with = client.chat.completions.create(
+    model="meta-llama/Llama-3.1-8B-Instruct",
+    messages=messages,
+    temperature=0,
+    extra_body={"continue_final_message": True},
+)
+print(response_with.choices[0].message.content)
+
+# Calling the API without continue_final_message (using default behavior).
+print("\n=== Prefill without continue_final_message ===")
+response_without = client.chat.completions.create(
+    model="meta-llama/Llama-3.1-8B-Instruct",
+    messages=messages,
     temperature=0,
 )
-
-print(response.choices[0].message.content)
+print(response_without.choices[0].message.content)
diff --git a/python/sglang/srt/openai_api/adapter.py b/python/sglang/srt/openai_api/adapter.py
index 8f74007fd..304a67ac1 100644
--- a/python/sglang/srt/openai_api/adapter.py
+++ b/python/sglang/srt/openai_api/adapter.py
@@ -950,9 +950,16 @@ def v1_chat_generate_request(
                                 openai_compatible_messages.append(
                                     {"role": message.role, "content": content["text"]}
                                 )
-                if openai_compatible_messages[-1]["role"] == "assistant":
-                    assistant_prefix = openai_compatible_messages[-1]["content"]
-                    openai_compatible_messages = openai_compatible_messages[:-1]
+                if (
+                    openai_compatible_messages
+                    and openai_compatible_messages[-1]["role"] == "assistant"
+                ):
+                    if request.continue_final_message:
+                        # Remove the final assistant message so its content can be continued.
+                        assistant_prefix = openai_compatible_messages[-1]["content"]
+                        openai_compatible_messages = openai_compatible_messages[:-1]
+                    else:
+                        assistant_prefix = None
                 else:
                     assistant_prefix = None
 
@@ -991,7 +998,33 @@ def v1_chat_generate_request(
                 modalities = []
             else:
                 conv = generate_chat_conv(request, chat_template_name)
-                prompt = conv.get_prompt()
+                # If we should continue the final assistant message, adjust the conversation.
+                if (
+                    request.continue_final_message
+                    and request.messages
+                    and request.messages[-1].role == "assistant"
+                ):
+                    # Remove the auto-added blank assistant turn, if present.
+                    if conv.messages and conv.messages[-1][1] is None:
+                        conv.messages.pop()
+                    # Rebuild the prompt from the conversation.
+                    prompt = conv.get_prompt()
+                    # Strip any trailing stop tokens or separators that indicate end-of-assistant.
+                    if isinstance(conv.stop_str, list):
+                        for stop_token in conv.stop_str:
+                            if prompt.endswith(stop_token):
+                                prompt = prompt[: -len(stop_token)]
+                    elif isinstance(conv.stop_str, str) and prompt.endswith(
+                        conv.stop_str
+                    ):
+                        prompt = prompt[: -len(conv.stop_str)]
+                    if conv.sep and prompt.endswith(conv.sep):
+                        prompt = prompt[: -len(conv.sep)]
+                    if getattr(conv, "sep2", None) and prompt.endswith(conv.sep2):
+                        prompt = prompt[: -len(conv.sep2)]
+                else:
+                    prompt = conv.get_prompt()
+
                 image_data = conv.image_data
                 audio_data = conv.audio_data
                 modalities = conv.modalities
@@ -1003,6 +1036,7 @@ def v1_chat_generate_request(
                     else:
                         stop.extend(request.stop)
                 prompt_ids = tokenizer_manager.tokenizer.encode(prompt)
+
         else:
             # Use the raw prompt and stop strings if the messages is already a string.
             prompt_ids = request.messages
diff --git a/python/sglang/srt/openai_api/protocol.py b/python/sglang/srt/openai_api/protocol.py
index ca27bf210..38b926c82 100644
--- a/python/sglang/srt/openai_api/protocol.py
+++ b/python/sglang/srt/openai_api/protocol.py
@@ -355,6 +355,7 @@ class ChatCompletionRequest(BaseModel):
     stop_token_ids: Optional[List[int]] = None
     no_stop_trim: bool = False
     ignore_eos: bool = False
+    continue_final_message: bool = False
     skip_special_tokens: bool = True
     lora_path: Optional[Union[List[Optional[str]], Optional[str]]] = None
     session_params: Optional[Dict] = None
diff --git a/test/srt/test_openai_server.py b/test/srt/test_openai_server.py
index 3488fee60..662ca0bde 100644
--- a/test/srt/test_openai_server.py
+++ b/test/srt/test_openai_server.py
@@ -534,6 +534,7 @@ The SmartHome Mini is a compact smart home assistant available in black or white
                 },
             ],
             temperature=0,
+            extra_body={"continue_final_message": True},
         )
 
         assert (