diff --git a/scripts/ci/ci_install_dependency.sh b/scripts/ci/ci_install_dependency.sh
index f36f59206..0e370eec3 100755
--- a/scripts/ci/ci_install_dependency.sh
+++ b/scripts/ci/ci_install_dependency.sh
@@ -74,7 +74,7 @@ fi
 $PIP_CMD list
 
 # Install additional dependencies
-$PIP_CMD install mooncake-transfer-engine==0.3.5 nvidia-cuda-nvrtc-cu12 py-spy huggingface_hub[hf_xet] $PIP_INSTALL_SUFFIX
+$PIP_CMD install mooncake-transfer-engine==0.3.6 nvidia-cuda-nvrtc-cu12 py-spy huggingface_hub[hf_xet] $PIP_INSTALL_SUFFIX
 
 if [ "$IS_BLACKWELL" != "1" ]; then
     # For lmms_evals evaluating MMMU
diff --git a/test/srt/hicache/test_hicache_storage_mooncake_backend.py b/test/srt/hicache/test_hicache_storage_mooncake_backend.py
new file mode 100644
index 000000000..fdfa8c93f
--- /dev/null
+++ b/test/srt/hicache/test_hicache_storage_mooncake_backend.py
@@ -0,0 +1,316 @@
+"""
+Benchmark tests for HiCache Storage with Mooncake backend.
+Usage:
+    python3.10 -m pytest test/srt/hicache/test_hicache_storage_mooncake_backend.py -v
+"""
+
+import json
+import os
+import subprocess
+import time
+import unittest
+from types import SimpleNamespace
+
+import requests
+from test_hicache_storage_file_backend import HiCacheStorageBaseMixin
+
+from sglang.test.few_shot_gsm8k import run_eval as run_eval_few_shot_gsm8k
+from sglang.test.test_utils import (
+    DEFAULT_MLA_MODEL_NAME_FOR_TEST,
+    CustomTestCase,
+    find_available_port,
+)
+
+
+class HiCacheStorageMooncakeBackendBaseMixin(HiCacheStorageBaseMixin):
+    """Base mixin class with common setup and utilities"""
+
+    # Default port ranges for Mooncake services - can be overridden in subclasses
+    mooncake_master_port_base = 50051
+    mooncake_metadata_port_base = 8080
+
+    @classmethod
+    def setUpClass(cls):
+        """Set up test environment and launch Mooncake services before server setup"""
+        # Find available ports for Mooncake services to avoid conflicts
+        cls.mooncake_master_port = find_available_port(
+            HiCacheStorageMooncakeBackendBaseMixin.mooncake_master_port_base
+        )
+        cls.mooncake_metadata_port = find_available_port(
+            HiCacheStorageMooncakeBackendBaseMixin.mooncake_metadata_port_base
+        )
+
+        # Start Mooncake services first
+        cls._start_mooncake_services()
+
+        # Call parent setup
+        super().setUpClass()
+
+    @classmethod
+    def tearDownClass(cls):
+        """Clean up Mooncake services after server teardown"""
+        # Call parent teardown first
+        super().tearDownClass()
+
+        # Stop Mooncake services
+        cls._stop_mooncake_services()
+
+    @classmethod
+    def _start_mooncake_services(cls):
+        """Start Mooncake metadata and master services with configurable ports and readiness detection"""
+        print("Starting Mooncake services...")
+        print(
+            f"Using master port: {cls.mooncake_master_port}, metadata port: {cls.mooncake_metadata_port}"
+        )
+
+        # Start metadata service with configurable port
+        try:
+            # Start metadata server with port configuration
+            cls.metadata_service_process = subprocess.Popen(
+                [
+                    "python3",
+                    "-m",
+                    "mooncake.http_metadata_server",
+                    "--port",
+                    str(cls.mooncake_metadata_port),
+                ],
+                stdout=subprocess.PIPE,
+                stderr=subprocess.PIPE,
+                preexec_fn=os.setsid,  # Create new process group
+            )
+            print(
+                f"Mooncake metadata service started on port {cls.mooncake_metadata_port}"
+            )
+        except (FileNotFoundError, subprocess.SubprocessError) as e:
+            print(f"Warning: Could not start Mooncake metadata service: {e}")
+            cls.metadata_service_process = None
+
+        # Start master service with configurable port
+        try:
+            # Start master server with port configuration
+            cls.master_service_process = subprocess.Popen(
+                ["mooncake_master", "--port", str(cls.mooncake_master_port)],
+                stdout=subprocess.PIPE,
+                stderr=subprocess.PIPE,
+                preexec_fn=os.setsid,  # Create new process group
+            )
+            print(f"Mooncake master service started on port {cls.mooncake_master_port}")
+        except (FileNotFoundError, subprocess.SubprocessError) as e:
+            print(f"Warning: Could not start Mooncake master service: {e}")
+            cls.master_service_process = None
+
+        # Wait for services to be ready instead of fixed sleep
+        cls._wait_for_mooncake_services_ready()
+
+    @classmethod
+    def _wait_for_mooncake_services_ready(cls, timeout: int = 30) -> bool:
+        """Wait for Mooncake services to be ready by checking their endpoints"""
+        print("Waiting for Mooncake services to be ready...")
+
+        start_time = time.time()
+        services_ready = False
+
+        while time.time() - start_time < timeout:
+            try:
+                # Check metadata service
+                metadata_ready = False
+                if (
+                    cls.metadata_service_process
+                    and cls.metadata_service_process.poll() is None
+                ):
+                    try:
+                        # Try to connect to the metadata service
+                        metadata_url = (
+                            f"http://127.0.0.1:{cls.mooncake_metadata_port}/metadata"
+                        )
+                        response = requests.get(metadata_url, timeout=2)
+                        if response.status_code == 200:
+                            metadata_ready = True
+                            print("Mooncake metadata service is ready")
+                    except (requests.RequestException, ConnectionError):
+                        # Service might not be fully started yet
+                        pass
+
+                # Check master service (if it has a health endpoint)
+                master_ready = False
+                if (
+                    cls.master_service_process
+                    and cls.master_service_process.poll() is None
+                ):
+                    # For now, we'll assume master service is ready if process is running
+                    # and it's been a few seconds since startup
+                    if (
+                        time.time() - start_time > 5
+                    ):  # Give master service time to initialize
+                        master_ready = True
+                        print("Mooncake master service is ready")
+
+                # Both services should be ready
+                if metadata_ready and master_ready:
+                    services_ready = True
+                    print("All Mooncake services are ready")
+                    break
+
+            except Exception as e:
+                print(f"Error checking service readiness: {e}")
+
+            time.sleep(2)
+
+        if not services_ready:
+            print(
+                "Warning: Mooncake services may not be fully ready, continuing anyway..."
+            )
+
+        return services_ready
+
+    @classmethod
+    def _stop_mooncake_services(cls):
+        """Stop Mooncake services"""
+        print("Stopping Mooncake services...")
+
+        # Stop metadata service
+        if hasattr(cls, "metadata_service_process") and cls.metadata_service_process:
+            try:
+                os.killpg(os.getpgid(cls.metadata_service_process.pid), 9)
+                cls.metadata_service_process.wait(timeout=5)
+                print("Mooncake metadata service stopped")
+            except (ProcessLookupError, subprocess.TimeoutExpired, OSError) as e:
+                print(f"Warning: Could not stop Mooncake metadata service: {e}")
+
+        # Stop master service
+        if hasattr(cls, "master_service_process") and cls.master_service_process:
+            try:
+                os.killpg(os.getpgid(cls.master_service_process.pid), 9)
+                cls.master_service_process.wait(timeout=5)
+                print("Mooncake master service stopped")
+            except (ProcessLookupError, subprocess.TimeoutExpired, OSError) as e:
+                print(f"Warning: Could not stop Mooncake master service: {e}")
+
+    @classmethod
+    def _get_additional_server_args_and_env(cls):
+        """Get additional server arguments specific to configuration - override in subclasses"""
+
+        server_args = {
+            "--tp-size": 1,
+            "--hicache-ratio": 2,
+            "--hicache-storage-backend": "mooncake",
+        }
+
+        # Set the environment variables for Mooncake using dynamic ports
+        env_vars = {
+            "MOONCAKE_MASTER": f"127.0.0.1:{cls.mooncake_master_port}",
+            "MOONCAKE_PROTOCOL": "rdma",
+            "MOONCAKE_DEVICE": "mlx5_roce0,mlx5_roce1",
+            "MOONCAKE_TE_META_DATA_SERVER": f"http://127.0.0.1:{cls.mooncake_metadata_port}/metadata",
+            "MOONCAKE_GLOBAL_SEGMENT_SIZE": "4294967296",  # 4 GiB
+        }
+
+        return server_args, env_vars
+
+
+'''
+# Same as #10131, layer first layout test TODO(mateng): will make it work
+class TestMooncakeBackendLayerFirstLayout(
+    HiCacheStorageMooncakeBackendBaseMixin, CustomTestCase
+):
+    """Layer first layout tests for HiCache-Mooncake backend"""
+
+    @classmethod
+    def _get_additional_server_args_and_env(cls):
+        """Get additional server arguments specific to configuration - override in subclasses"""
+        server_args, env_vars = super()._get_additional_server_args_and_env()
+        server_args["--hicache-mem-layout"] = "layer_first"
+        server_args["--hicache-io-backend"] = "direct"
+        return server_args, env_vars
+'''
+
+
+class TestMooncakeBackendPageFirstLayout(
+    HiCacheStorageMooncakeBackendBaseMixin, CustomTestCase
+):
+    """Page first layout tests for HiCache-Mooncake backend"""
+
+    @classmethod
+    def _get_additional_server_args_and_env(cls):
+        """Get additional server arguments specific to configuration - override in subclasses"""
+        server_args, env_vars = super()._get_additional_server_args_and_env()
+        server_args["--hicache-mem-layout"] = "page_first"
+        return server_args, env_vars
+
+
+class TestMooncakeBackendMLAModel(
+    HiCacheStorageMooncakeBackendBaseMixin, CustomTestCase
+):
+    """MLA Model tests for HiCache-Mooncake backend"""
+
+    @classmethod
+    def _get_model_name(cls):
+        """Use MLA model for testing"""
+        return DEFAULT_MLA_MODEL_NAME_FOR_TEST
+
+    @classmethod
+    def _get_additional_server_args_and_env(cls):
+        """Get additional server arguments specific to configuration - override in subclasses"""
+        server_args, env_vars = super()._get_additional_server_args_and_env()
+        server_args["--hicache-mem-layout"] = "page_first"
+        server_args["--tp-size"] = 2
+        return server_args, env_vars
+
+
+class TestMooncakeBackendAccuracy(
+    HiCacheStorageMooncakeBackendBaseMixin, CustomTestCase
+):
+    """Accuracy tests for HiCache-Mooncake backend"""
+
+    @classmethod
+    def _get_additional_server_args_and_env(cls):
+        """Get additional server arguments specific to configuration - override in subclasses"""
+        server_args, env_vars = super()._get_additional_server_args_and_env()
+        server_args["--hicache-ratio"] = 1.5
+        server_args["--tp-size"] = 2
+        return server_args, env_vars
+
+    def test_eval_accuracy(self):
+        """Test eval accuracy with cache persistence across cache flushes"""
+        print("\n=== Testing Eval Accuracy with Cache Persistence ===")
+
+        # First evaluation - populate cache
+        print("Phase 1: Running initial GSM8K evaluation to populate cache...")
+        args_initial = SimpleNamespace(
+            num_shots=5,
+            data_path=None,
+            num_questions=50,
+            max_new_tokens=512,
+            parallel=10,
+            host=f"http://{self.base_host}",
+            port=int(self.base_port),
+        )
+        metrics_initial = run_eval_few_shot_gsm8k(args_initial)
+
+        # Flush cache to force remote storage access
+        print("Phase 2: Flushing device cache...")
+        self.assertTrue(self.flush_cache(), "Cache flush should succeed")
+        time.sleep(2)
+
+        # Second evaluation - should use remote cache
+        print("Phase 3: Running second GSM8K evaluation using remote cache...")
+        metrics_cached = run_eval_few_shot_gsm8k(args_initial)
+
+        # Verify accuracy consistency
+        accuracy_diff = abs(metrics_initial["accuracy"] - metrics_cached["accuracy"])
+        print(f"Accuracy difference: {accuracy_diff:.4f}")
+
+        # Assertions
+        self.assertGreater(
+            metrics_initial["accuracy"], 0.6, "Initial accuracy should be reasonable"
+        )
+        self.assertGreater(
+            metrics_cached["accuracy"], 0.6, "Cached accuracy should be reasonable"
+        )
+        self.assertLess(
+            accuracy_diff, 0.05, "Accuracy should be consistent between cache states"
+        )
+
+
+if __name__ == "__main__":
+    unittest.main(verbosity=2)
diff --git a/test/srt/run_suite.py b/test/srt/run_suite.py
index 912d32801..13d1000a3 100644
--- a/test/srt/run_suite.py
+++ b/test/srt/run_suite.py
@@ -142,6 +142,7 @@ suites = {
     "per-commit-8-gpu": [
         # Disabled because it hangs on the CI.
         # TestFile("ep/test_moe_ep.py", 181),
+        TestFile("hicache/test_hicache_storage_mooncake_backend.py", 800),
         TestFile("lora/test_lora_llama4.py", 600),
         TestFile("test_disaggregation.py", 499),
         TestFile("test_disaggregation_different_tp.py", 155),