diff --git a/python/sglang/srt/custom_op.py b/python/sglang/srt/custom_op.py
index 39c1c2681..5b502a153 100644
--- a/python/sglang/srt/custom_op.py
+++ b/python/sglang/srt/custom_op.py
@@ -1,11 +1,12 @@
 from torch import nn
 
-from sglang.srt.utils import cpu_has_amx_support, is_cpu, is_cuda, is_hip
+from sglang.srt.utils import cpu_has_amx_support, is_cpu, is_cuda, is_hip, is_npu
 
 _is_cuda = is_cuda()
 _is_hip = is_hip()
 _is_cpu = is_cpu()
 _is_cpu_amx_available = cpu_has_amx_support()
+_is_npu = is_npu()
 
 
 class CustomOp(nn.Module):
@@ -60,6 +61,9 @@ class CustomOp(nn.Module):
     def forward_cuda(self, *args, **kwargs):
         raise NotImplementedError
 
+    def forward_npu(self, *args, **kwargs):
+        raise NotImplementedError
+
     def forward_hip(self, *args, **kwargs):
         return self.forward_cuda(*args, **kwargs)
 
@@ -79,5 +83,7 @@ class CustomOp(nn.Module):
             return self.forward_hip
         elif _is_cpu and _is_cpu_amx_available:
             return self.forward_cpu
+        elif _is_npu:
+            return self.forward_npu
         else:
             return self.forward_native
diff --git a/python/sglang/srt/layers/activation.py b/python/sglang/srt/layers/activation.py
index a9e3436a6..d84d3eda5 100644
--- a/python/sglang/srt/layers/activation.py
+++ b/python/sglang/srt/layers/activation.py
@@ -48,6 +48,9 @@ if _is_cuda:
 
 logger = logging.getLogger(__name__)
 
+if is_npu():
+    import torch_npu
+
 
 class SiluAndMul(CustomOp):
     def forward_native(self, x: torch.Tensor) -> torch.Tensor:
@@ -70,6 +73,10 @@ class SiluAndMul(CustomOp):
         else:
             return self.forward_native(x)
 
+    def forward_npu(self, x: torch.Tensor) -> torch.Tensor:
+        out = torch_npu.npu_swiglu(x)
+        return out
+
 
 class GeluAndMul(CustomOp):
     def __init__(self, approximate="tanh"):
diff --git a/python/sglang/srt/layers/layernorm.py b/python/sglang/srt/layers/layernorm.py
index 2277a70af..5d8106f17 100644
--- a/python/sglang/srt/layers/layernorm.py
+++ b/python/sglang/srt/layers/layernorm.py
@@ -52,6 +52,9 @@ elif _is_hip:
 
 logger = logging.getLogger(__name__)
 
+if is_npu():
+    import torch_npu
+
 
 class RMSNorm(CustomOp):
     def __init__(
@@ -76,6 +79,18 @@ class RMSNorm(CustomOp):
         out = rmsnorm(x, self.weight.data, self.variance_epsilon)
         return out
 
+    def forward_npu(
+        self,
+        x: torch.Tensor,
+        residual: Optional[torch.Tensor] = None,
+    ) -> Union[torch.Tensor, Tuple[torch.Tensor, torch.Tensor]]:
+        if residual is not None:
+            out, _, residual_out = torch_npu.npu_add_rms_norm(
+                residual, x, self.weight.data, self.variance_epsilon
+            )
+            return out, residual_out
+        return torch_npu.npu_rms_norm(x, self.weight.data, self.variance_epsilon)[0]
+
     def forward_aiter(
         self,
         x: torch.Tensor,
diff --git a/python/sglang/srt/layers/rotary_embedding.py b/python/sglang/srt/layers/rotary_embedding.py
index bd145a4b0..f931098be 100644
--- a/python/sglang/srt/layers/rotary_embedding.py
+++ b/python/sglang/srt/layers/rotary_embedding.py
@@ -8,7 +8,14 @@ import torch
 import torch.nn as nn
 
 from sglang.srt.custom_op import CustomOp
-from sglang.srt.utils import cpu_has_amx_support, is_cpu, is_cuda, is_hip, is_npu
+from sglang.srt.utils import (
+    cpu_has_amx_support,
+    get_bool_env_var,
+    is_cpu,
+    is_cuda,
+    is_hip,
+    is_npu,
+)
 
 _is_cuda = is_cuda()
 _is_hip = is_hip()
@@ -19,6 +26,9 @@ _is_cpu = is_cpu()
 if _is_cuda:
     from sgl_kernel import apply_rope_with_cos_sin_cache_inplace
 
+if is_npu():
+    import torch_npu
+
 
 def _rotate_neox(x: torch.Tensor) -> torch.Tensor:
     x1 = x[..., : x.shape[-1] // 2]
@@ -152,6 +162,36 @@ class RotaryEmbedding(CustomOp):
         key = torch.cat((key_rot, key_pass), dim=-1).reshape(key_shape)
         return query, key
 
+    def forward_npu(
+        self,
+        positions: torch.Tensor,
+        query: torch.Tensor,
+        key: torch.Tensor,
+        offsets: Optional[torch.Tensor] = None,
+    ) -> Tuple[torch.Tensor, torch.Tensor]:
+        """A PyTorch-npu implementation of forward()."""
+        import os
+
+        if get_bool_env_var("SGLANG_ENABLE_TORCH_COMPILE"):
+            return self.forward_native(positions, query, key, offsets)
+        else:
+            rotary_mode = "half"
+            if self.is_neox_style:
+                rotary_mode = "half"
+            else:
+                rotary_mode = "interleave"
+            mrope_section = [0, 0, 0]
+            query_out, key_out = torch_npu.npu_mrope(
+                positions,
+                query,
+                key,
+                self.cos_sin_cache,
+                self.head_size,
+                mrope_section=mrope_section,
+                rotary_mode=rotary_mode,
+            )
+            return query_out, key_out
+
     def forward_cpu(
         self,
         positions: torch.Tensor,